Johns Hopkins: Cervical fluid samples gathered during routine Papanicolaou (Pap) tests are the basis of a new screening test for endometrial and ovarian cancers developed by researchers at the Johns Hopkins Kimmel Cancer Center. PapSEEK detects mutations in DNA that have been identified for specific cancers sooner. Earlier detection of cancer could lead to earlier treatment and potentially better outcomes for patients. The test uses cervical fluid samples to look for mutations in 18 genes, which are highly or commonly mutated in endometrial or ovarian cancers, and aneuploidy, the presence of abnormal numbers of chromosomes in cells. The researchers said their results showed the potential for mutation-based diagnostics to detect endometrial and ovarian cancers earlier.
Georgia: Reducing the calories healthy adults consume — without causing malnutrition — may also reduce oxidative stress, and in turn prevent aging, according to a recent study led by a researcher from the School of Public Health at Georgia State University. The study measured chemical signs of wear and tear on the body over time, known as oxidative stress, and found that over two years subjects who reduced their caloric intake by approximately 12 percent showed fewer chemical signs of oxidative stress than subjects who did not.